Colossal spider venom
From NWNWiki
Initial effect: Lowers strength by 2 to 16 (2d8).
Secondary effect: Lowers strength by 2 to 16 (2d8).
Save DC: 35
Handle DC: 28
Colossal spider venom is resisted upon contraction if the target makes a successful fortitude saving throw. If the save fails, the initial effect is applied, and one minute later a second saving throw is attempted to avoid the secondary effect.
